Message: #64308
Юля Смоленск » 26 Jan 2017, 21:06
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Non-Steroidal Anti-Inflammatory Drugs

Movement is the joy of being. But for people whose joints hurt, movement brings pain and grief. With age, the human musculoskeletal system wears out, chronic joint diseases occur, such as arthritis, arthrosis, and osteochondrosis. To prevent this from happening prematurely, it is necessary to take preventive measures at the first signs of degenerative changes in the joints: therapeutic exercises for the joints, a diet for the joints and the musculoskeletal system as a whole, Ayurvedic drugs for the treatment of articular diseases, folk methods for treating the skeletal system (so, to For example, it is believed that a solid-colored blue candle, or rather its burning and the emitted spectrum, contributes to the speedy fusion of fractures), medications and medicines for the treatment of diseases of the musculoskeletal system. A new physiotherapy methodology – laser shock wave therapy allows you to rejuvenate the joints and prevent their destruction as a result of acquired chronic diseases.

The category of drugs that affect the joints include:

Non-steroidal anti-inflammatory drugs, as well as anti-rheumatic drugs:

Non-steroidal anti-inflammatory drugs are a group of drugs that have a pronounced analgesic, antipyretic, and anti-inflammatory effect. The drugs relieve pain, fever and inflammation of diseased joints. In their properties, nonsteroidal drugs differ from steroids, hence the emphasis on the term nonsteroidal.

The group of non-steroidal anti-inflammatory drugs is the backbone on which rheumatology is based. Non-steroidal drugs contribute to the healing process of most diseases of the musculoskeletal system. The cause of diseases of the joints (arthritis, polyarthritis, gouty arthritis), and the entire musculoskeletal system is chronic foci of inflammation.

The mechanism of action of non-steroidal anti-inflammatory drugs and their analogues is associated with the inhibition (restraint) of such an enzyme as COX, it is COX that triggers the reaction of prostaglandin synthesis from arachidonic acid, which causes the process of inflammation of the joint. Thus, non-steroidal anti-inflammatory drugs reduce the intensity the production of prostaglandins, this explains the anti-inflammatory effect of non-steroidal drugs, and this also causes side effects such as exacerbation of gastritis, peptic ulcers and gastric bleeding. This fact causes a surge in scientific development of new types of non-steroidal anti-inflammatory drugs that have a pronounced anti-inflammatory and analgesic efficacy with a minimum number of adverse reactions.

After the extraction of acetylsalicylic acid from willow bark in 1829, non-steroidal anti-inflammatory drugs began to be widely used in the treatment of diseases of the musculoskeletal system and joints, manifested by pain or inflammation. A significant part of non-steroidal drugs are considered quite safe and are sold in pharmacies without prescriptions.

Most often, non-steroidal anti-inflammatory drugs are prescribed for the following painful conditions:

Rheumatoid arthritis;
Gout;
Dysmenorrhea;
Bone metastases accompanied by pain;
Headache and migraine;
Postoperative pain syndrome;
Pain syndrome of mild or moderate severity with inflammatory changes or trauma;
Fever;
Renal colic;
Non-steroidal anti-inflammatory drugs are contraindicated in erosive and ulcerative lesions of the gastrointestinal tract, especially in the acute stage, severe violations of the liver and kidneys, with individual intolerance, pregnancy, breastfeeding.

Non-steroidal anti-inflammatory drugs should be taken with caution in patients with bronchial asthma.

For people with hypertension or heart failure, nonsteroidal anti-inflammatory drugs (NSAIDs) that have minimal effect on renal blood flow should be selected.

In the elderly, it is necessary to strive for the appointment of minimal doses to achieve results and short courses of nonsteroidal drugs.

The joints begin to ossify if calcium or uric acid salts are deposited in them, for example, with gout. For the treatment of joints, it is necessary to go through 3 stages of treatment: treatment in a hospital, treatment in specialized sanatoriums, preventive procedures that can be carried out independently, at home. If you combine medications with manual therapy, acupuncture, acupuncture, magnetotherapy, physiotherapy and exercise therapy, even complete healing is possible.

If the patient is noted to have an acute form of the disease, inflammation is initially relieved, for example, by taking Swedish Bitters or other herbal preparations. If a chronic disease manifests itself, first of all, they restore the working capacity and mobility of the joint and prevent further attacks.

Non-steroidal drugs will protect you from inflammation, fever, redness, pain and swelling.

However, you should not combine several drugs that are homogeneous in their chemical composition. It is better to increase the amount of non-steroidal drug.

Consider a group of non-steroidal anti-inflammatory drugs and their analogues.

Aertal. Aertal’s analogues are: Diclotol, Zerodol, Infenac, Nayzilat. All these remedies are used in rheumatism. These NSAIDs (non-steroidal anti-inflammatory drugs) relieve pain and relieve fever, relieve pain and reduce inflammation.

Dolaren. Dolaren analogues: Neurodiclovit, Olfen -100 rectocaps, Fanigan, Flamidez, Bol-ran, Diclocaine, Diclofenac with paracetamol, Dolar, Dopex, Maxigezik. Cinepar. All of these non-steroidal anti-inflammatory drugs combined drugs are quite effective in rheumatism, effectively relieve fever;

Ibuprofen. Ibuprofen analogues used in diseases of the joints: Bofen, Ibufen for children. Ibufen forte. Ibufen junior, Imet, Nurofen, Nurofen for children, Nurofen forte, Nurofen express, Nurofen express ultra, Brufen, Ibunorm, Ibonurm baby, Ibuprom sprint. Caps, Ibutard 300, Irfen-200, Orafen, Faspik, Brustan. Ibuprofen and its analogues are also effective for eliminating toothache and headaches;

Indomethacin Sopharma: Analogues of indomethacin: Indomethacin – retard, medintol retard;

Ketorolac – Health. Ketorolac taxes: Ketalgin long, Ketanov, Ketorolong – Darnitsa, Ketolac, Ketorol, Ketorolac – Kredopharm. Ketorolac is not intended for long-term use.

Meloxicam. Analogues of meloxicam are such drugs to reduce pain in the treatment of the musculoskeletal system: Melbek, Movalis, Moviksikam, Aspikam, Melox, Meloxicam Sopharma, Movalkin, Meloxicam-Astrapharm, Meloxicam – Lugal, Movalgin, Revmoxicam, Recox. Meloxicam, which belongs to non-steroidal anti-inflammatory drugs, is prescribed for inflammation of the joints, has a pronounced analgesic effect;

Nalgezin. Analogues of nalgezin: Nalgezin forte, Nproff, Promax, Ketonal, Mazhezik-Sanovel, Zotek, Dexalgin, Dexaldin injection, Depiofen, Mefenamic acid – Darnitsa; Nalgesin relieves gout attacks well, in case of an acute attack, one and a half tablets of nalgesin should be taken, which is 825 mg, then take 275 mg, which is half a tablet 8 hours before the end of the attacks. The daily dose of nalgesin should not exceed 1375 mg.

Nimesulide. Analogues of the medicine nimesulide: nimegezik, Nimesil, Nimid, Affida fort, Nise, Nimesin, Nimeslud _Darnitsa, Nimesulide – Phytopharm, Nimulid, Remesulide, Toro-Sanovel, Nimid forte, Nanogan, Oksigan, Sigan. Nemesulide is a very common non-steroidal anti-inflammatory drug for relieving joint pain caused by dysfunction of the musculoskeletal system as a result of gout, bursitis of various genesis, pain syndromes of various etiologies. Nemisulide is used for inflammatory processes in gynecology, febrile conditions, tonsillitis. Nemisulide may displace other drugs from their binding sites due to its proximity to plasma proteins.

Piroxicam. Piroxicam analogues: Piroxicam Sopharma, Fedim-20, Texamen-L, Xefocam, Xekofam Rapid, Lorakam – 4, Lorakam -8;

Revmoksib. Analogues of the drug rheumoxib: Celebrex, Rancelex, Flogoxib-Health, Deneble, Dinanstat, Arcoxia, Exinef, Synmeton, Flekcerin, Dimax, Orcerin.

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