as they provide a substantial evidence base and show the cardinal benefit and utility as a nutraceutical. Elevated plasma levels of agmatine deiminase in patients with schizophrenia [4] Preclinical studies have shown that agmatine may play an important role in pathological physiology schizophrenia. This study was designed to study plasma agmatine deiminase in patients with schizophrenia and healthy controls. For the study, 18 patients with schizophrenia and 19 people without any health problems were selected. Plasma levels of agmatine deiminase were measured using HPLC (high performance liquid chromatography), which allowed the separation of mixtures of complex substances for analysis. The level of protein S100B, which is a peripheral biomarker of brain damage, was measured using the ELISA method or enzyme immunoassay. I will not go deep into the intricacies of the experiment, but simply write down its result. Результаты клинических исследований подтверждают гипотезу о том, что повышенный уровень агматина может быть показателем прогрессии (появлении) schizophrenia. Результаты исследования также предполагают, что уровень агматина в крови может быть потенциальным биомаркером schizophrenia. Conclusions Agmatine is a promising drug, both in the sports environment and in the field of medicine. An ever-increasing amount of research each time discovers its new properties, in connection with which, more and more potential areas of its application are revealed. What more can be said? Do not overestimate this substance, as at the moment there are not enough clinical studies on the basis of which it would be possible to say for sure that this is a really worthwhile supplement. In addition, most of the experiments were carried out on animals, also by injection (in most cases). That is, the supplement, which is now present in the form of capsules, cannot guarantee the positive results that were listed above in the article. This is due to the fact that the oral method of taking the supplement can have a completely different effect, or not give any results at all. In general, we wait, hope and believe that in the near future there will still be some significant evidence base based on all kinds of studies ... In addition, at the moment we can say that the currently known mechanisms of its action make the drug more interesting for people, who are interested in the overall improvement of their physical and mental health, rather than bodybuilders aimed at intensive muscle gain and fat burning. Simply put, if you are thinking of getting some kind of profit from this supplement in the form of increasing protein synthesis or improving and accelerating lipolysis, then agmatine is not for you. At least for now. Maybe they will invent some kind of powerful additive by adding some additional components. ECA is an example. Here are the things! I hope everyone was interested in reading about Agmatine and learning something new about this substance. Thank you all for your attention!